Present asthma research is focused on chronic inflammation and remodelling of airways. Leukotrienes take part in the remodelling process due to their direct effects on smooth muscle cells, eosinophils, epithelial cells, and other cell types. Leukotriene antagonists constitute a totally novel focus for processing inflammation by selective inhibition leukotriene effects....
The Cecropia obtusifolia tree, popularly known as guarumbo in Mexico, is used in folk medicine for treatment of type 2 diabetes mellitus (DM2). C. obtusifolia’s antidiabtic effect was assessed in animal models, as well as in humans and attributed to chlorogenic acid (CA) and isoorientine (ISO). The aim of this...