High fructose intake through sugar-sweetened beverages induces metabolic and endocrine changes in adipose tissue (AT). It has been suggested that microRNAs (miRNAs) contained in extracellular vesicles (EVs) are some of the endocrine signals secreted by adipocytes, which can regulate diverse cellular processes, including adipocyte differentiation and metabolism. However, the effect...
La inflamación es un proceso fisiológico protector que se activa en respuesta a una agresión físico-química para el restablecimiento del tejido afectado. En la inflamación, los macrófagos juegan un papel crítico mediante la producción de citocinas. Una respuesta inflamatoria excesiva y prolongada puede conducir a enfermedades asociadas al síndrome metabólico,...
Eicosapentaenoic acids (EPA) and docosahexaenoic (DHA) are omega-3 polyunsaturated fatty acids With the beneficial effects on preventing various diseases in which the inflammation plays a fundamental role. Since these omega - 3 fatty acids are ligands for PPARs, they could have an impact on metabolic activity. Therefore, they could exert...
Diabetes mellitus (DM) is one of the main chronic diseases at the present time and it is widespread throughout the world. It is defined as a set of metabolic disorders whose main characteristic is a persistent high blood glucose concentration (hyperglycemia), abnormal until reaching concentrations harmful to the physiological systems,...