Biosensor technology has great potential for the detection of cancer through tumor-associated molecular biomarkers. In this work, we describe the immobilization of the recombinant humanized anti-HER2 monoclonal antibody (trastuzumab) on a silver nanostructured plate made by pulsed laser deposition (PLD), over a thin film of Au(111). Immobilization was performed via...
Gold nanoparticles (AuNP) play an important role against breast cancer while serving as an excellent marker for early diagnosis, chemotherapy drugs and genes regulator. Understanding the interaction of AuNP with the cell surface and changes in the biomechanical properties of the plasma membrane of cancer cells is essential for the...