Osteosarcopenic obesity (OSO) has been associated with immobility, falls, fractures, and other dysfunctions, which could increase mortality risk. However, its etiology remains unknown. Recent studies revealed that sedentarism, fat gain, and epigenetic regulators are critical in its development. One effective intervention to prevent and treat OSO is exercise. Therefore, in...
In aging, changes in body composition occur even without significant changes in the body mass index (BMI), which generate a decrease in strength and mobility in the elderly, conditioning them to sedentary lifestyle. The increase in body fat, the decrease in muscle mass and bone mineral density lead to the...