Neurogenesis in the dentate gyrus (DG) of the hippocampus is increased by spatial learning and postnatal stimulation. Conversely, prenatal stress (PS) produces a decrease in the proliferation of hippocampal granular cells. This work evaluated the effect of postnatal tactile stimulation (PTS), when applied from birth to adulthood (3 months old),...
Prenatal stress causes spatial learning and memory deficits at any stage of postnatal life by modifying hippocampal function. Serotonergic and noradrenergic axon terminals, involved in cognitive processes, are present the hippocampus. Despite studies about the participation of both neurochemical systems in cognitive processes, it is currently unknown whether prenatal stress...
Major depressive disorder or major depression is a common disorder that affects people worldwide and combines symptoms at psychological, physiological, and behavioural level. This disorder is predicted to be the second caus e of disability in 2020. Animal models of major depression caused by stress are relevant for the better...