El cáncer cervicouterino (CaCu) es el segundo cáncer más común en el mundo que ocurre en la población femenina. La mayoría de los casos de CaCu se diagnostican en estadios avanzados. Por lo tanto, la radioterapia es la modalidad terapéutica más utilizada. El mecanismo de acción de la radiación ionizante...
Loss of function of the p53 tumor suppressor due to mutations causes genomic instability in cancer cells. Mutations of p53, which occur in more than 50% of all human cancers, are characterized by a gain of oncogenic function and loss of wildtype p53 function in cancer cells. Centrosome amplification is...
Cervical cancer (CaCu) is a serious public health problem, being the second cause of death in women from cancer in Mexico. One of the main drugs used in chemotherapy against CaCu is cisplatin; however, it has the disadvantages of high toxicity in patients and some cases it usually generates chemoresistance....