The growth differentiation factor 11 (GDF11) promotes the loss of an aggressive phenotype in various tumors, which has been studied in our research group using cell lines derived from hepatocellular carcinoma (HCC). Due to this loss in aggressiveness directly in transformed cells, in the present work, we focus on the...
Meduloblastoma is the most common malignant brain tumor developed during childhood and it accounts for 20% of total pediatric brain tumors. It is originated in the cerebellum, but it can invade other central nervous system regions. Besides tumoral cells, medulloblastoma is also composed by many groups of heterogeneous transformed cells....
Inflammation is an adaptative response, triggered by various harmful stimuli, its aim is to eliminate injurious agents, as well as the restoration and normal functioning of the affected tissue or organ. However, this response can be altered and produce permanent damage, which often have pathological consequences, like cardiovascular, respiratory, digestive...
La obesidad es una de las enfermedades crónico-degenerativas más comunes a nivel mundial y nacional. Es el principal factor de riesgo para desarrollar padecimientos como la Diabetes Tipo 2 (DT2), hipertensión, complicaciones cardiovasculares e incluso algunos tipos de cáncer. Su etiología es multifactorial, entre los factores que caracterizan su desarrollo...
