Trypanosoma cruzi es el agente etiológico de la enfermedad de Chagas, es transmitido a través del contacto con la materia fecal de un triatomino infectado. El diagnóstico de esta parasitosis se realiza mediante la detección de anticuerpos específicos en suero, sin embargo, existen reacciones falsas positivas o reacciones cruzadas con...
Chagasí disease contributes significantly to cardiovascular morbidity and mortality in several Latin-American countries. Chronic human Chagas' disease ranges from an asymptomatic to a severe cardiac clinical form. The involvement of the host's immune response in the development and maintenance of chagasic pathology has been demonstrated by several groups. Chronic cardiac...
American Trypanosomiasis is a parasitic disease caused by the protozoan Trypanosoma cruzi. Benznidazole and nifurtimox are drugs that have been used for its therapy; nevertheless, they have collateral effects in long-term treatments. NADHfumarate reductase is a potential pharmacological target since it is essential for the survival of parasites and is...
In Mexico, the maternal-fetal transmission of Trypanosoma cruzi has been little studied, the first case was published in 1998 and to date there are no more official reports. We determinate the T. cruzi infection prevalence in 1448 pregnant women from Oaxaca state, Jalisco state and Mexico City, as well as...