The main purpose of this research was to describe electroencephalographic activity during sleep and the cyclical alternating pattern (CAP) in patients with idiopathic insomnia. It included 22 patients (8 male, 14 female) with a diagnosis of idiopathic insomnia, ranging in age from 19 to 45 years old, the average being...
El sueño constituye un factor importante para la restitución corporal y la consolidación de la memoria. La pérdida del sueño puede conducir a distintos problemas de salud como infarto, diabetes y presión arterial alta. La privación del sueño impacta negativamente en el funcionamiento humano afectando los niveles de alerta y...
La barrera hematoencefálica es un sistema constituido de células endoteliales, astrocitos, pericitos y microglia que mantienen la alostasis del sistema nervioso central. Todos los elementos de la barrera hematoencefálica son importantes para el funcionamiento del sistema pero las células endoteliales le confieren las propiedades físicas y químicas de barrera. Las...
Sleep is an indispensable physiological activity, it is considered that the human being spends a third of his life sleeping, which indicates that the functions of sleep are of vital importance. Although the function of sleep is not fully described, several theories are considered, among them, it deters the regulation...
Sleep loss produces blood-brain barrier (BBB) hyperpermeability by increasing endocytosis and promoting tight junction disassemble. Similar effects have been reported in mice with pericyte deficiency. In previous studies, we showed that pericytes seem to detach from the capillary wall in sleep-restricted animals. Thus, we aimed to evaluate the changes in...